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Research lab

Harvard Medical School

Harvard Medical School is Harvard University's graduate school for medicine and biomedical research, encompassing the Blavatnik Institute.

Known aliases

  • Blavatnik Institute at HMS
  • Harvard University
  • HMS

Current stories

leadershipOne report1 publisher

AI mammogram risk scores climbed for six years before breast cancer diagnosis in a 54,014-woman study

AI risk scores read from mammograms rose from a median 2.1 to 6.6 over the six years before breast cancer diagnosis in a Radiology study of 54,014 women. The retrospective result supports tracking each woman's score across screening rounds and leaves open what a rise should trigger.

Publishers:rsna.org

Reality

Evidence50
Adoption
Not scored
Hype gap+35
Incentives60
Confidence45
scienceOne report1 publisher

Finding the fetal hemoglobin switch that Casgevy edits wins five scientists the 2026 Alpert Prize

Five Harvard and NIH scientists won the 2026 Warren Alpert Foundation prize for BCL11A work that led to Casgevy, the first CRISPR medicine. The prize honours genetics that took decades to reach patients, at a time when cost and conditioning toxicity limit how many people receive the edit.

Publishers:genengnews.com

Reality

Evidence45
Adoption25
Hype gap+20
Incentives
Not scored
Confidence50
scienceConfirmed3 publishers

In mice and 11 patients, transplanted hearts moved toward their hosts' biological age

Jesse Poganik's Harvard group reports that donor hearts shifted toward their recipients' biological age in mice and in 11 human transplants. The bioRxiv preprint has not been peer reviewed, so it is enough to question the under-45 donor preference but not to rewrite it.

Perspective Coverage

3 publishers
Builder
Builder 45%
Operator
Operator 43%
Investor
Investor 12%

Reality

Evidence45
Adoption
Not scored
Hype gap+30
Incentives
Not scored
Confidence55
scienceOne report1 publisher

MitoCarta's survey of five parasites and a plant finds proteins absent from human mitochondria

Broad Institute-led researchers have catalogued mitochondrial proteins in one plant and five human parasites across nine papers in Cell and related journals. Parasite proteins that human mitochondria lack give neglected tropical disease programs a first list of candidate drug targets to test.

Publishers:phys.org

Reality

Evidence50
Adoption
Not scored
Hype gap+20
Incentives55
Confidence55
scienceOne report1 publisher

Cryo-ET catches a rotavirus punching into a cell with a calcium-triggered pore

Stephen Harrison's Harvard lab imaged a rotavirus breaking into a cell and found that VP7, not the protein he expected, forms the pore that releases its genome. The team reported the mechanism Sept. 10 in Science, and Harrison sees it as a lead on delivering large gene therapies into cells.

Publishers:phys.org

Reality

Evidence62
Adoption
Not scored
Hype gap+8
Incentives60
Confidence55
scienceOne report1 publisher

Cells catch fusing viruses by spilling their own DNA, Harvard team finds

Harvard Medical School researchers found that a virus fusing with a cell ruptures the nucleus, spilling host DNA that trips the cGAS alarm within an hour. The team says the work could inform how viral-vector gene therapies and vaccines are designed.

Publishers:phys.org

Reality

Evidence55
Adoption
Not scored
Hype gap+15
Incentives
Not scored
Confidence50
scienceOne report1 publisher

Eight weeks of diet, exercise and sleep advice matched CBT in 267 depressed adults

In a Deakin University trial, an independent rater scored the lifestyle arm 8.55 points down on a 60-point depression scale against 6.82 for CBT, clearing a non-inferiority margin the team set at 1.6 points before randomisation.

Publishers:newscientist.com

Reality

Evidence58
Adoption
Not scored
Hype gap+12
Incentives45
Confidence55
scienceOne report1 publisher

MIT pairs Raman spectra with single-cell sequencing on the same cells to barcode senescence

The MIT group measured skin and lung cells from 2-month-old and 26-month-old mice both ways at once, using the destructive sequencing read to label the optical one. Human tissue, the authors say, is next.

Publishers:genengnews.com phys.org

Reality

Evidence52
Adoption8
Hype gap+28
Incentives58
Confidence62
scienceOne report1 publisher

A five-minute per-patient fit puts MIT's X-ray-to-CT registration under a millimeter

Existing 2D/3D registration models align well for some patients and fail for others. MIT's xvr, out today in Nature, fits itself to one patient in about five minutes, then matches that patient's X-rays to their 3D scan in seconds.

Publishers:news.mit.edu

Reality

Evidence58
Adoption
Not scored
Hype gap+30
Incentives70
Confidence55
scienceOne report1 publisher

Harvard logs 30,000 chimeric mRNAs, some building proteins from two genes

Direct RNA sequencing turned up a library of hybrid transcripts in mammalian cells, almost 400 of them responsive to inflammatory signals. The one-gene-one-protein reference list has no slot for any of them.

Publishers:phys.org

Reality

Evidence58
Adoption14
Hype gap+26
Incentives70
Confidence46
scienceOne report1 publisher

Siderophore-engineered bacteria weather olivine 2.6 times faster in flowing seawater

Enhanced rock weathering's problem has always been rate rather than chemistry, and a Nature Biotechnology result attacks the rate directly. The 2.6-fold gain was measured on kilograms of mineral in a flow reactor.

Publishers:genengnews.com

Reality

Evidence52
Adoption12
Hype gap+44
Incentives58
Confidence50
productOne report1 publisher

Engineered ocean bacterium strips the rust that stalls carbon-capturing olivine

The 2.6-fold speedup came from deleting the microbe's own off switch. That leaves the hard part of this work to whoever writes the discharge permit for a basin full of it.

Reality

Evidence42
Adoption8
Hype gap+60
Incentives66
Confidence38
scienceOne report1 publisher

Specialists outbilled primary care doctors on Medicare's new relationship-care add-on

Medicare's G2211 code paid $16 extra for ongoing, relationship-based care and drew 26 million claims in its first year. Claims volume, though, is the one thing a fee-schedule tweak is guaranteed to move.

Publishers:statnews.com

Reality

Evidence55
Adoption78
Hype gap+18
Incentives62
Confidence52
scienceOne report1 publisher

The Pentagon wants to test soldiers' testosterone. The label for treating it is narrow.

Scientific American asked endocrinologists what testosterone therapy actually does for cisgender men. The approved use is tightly bounded; the demand, and now the policy, is not.

Reality

Evidence62
Adoption32
Hype gap+55
Incentives58
Confidence55
scienceOne report1 publisher

Harvard's KinoPlex cuts 1.8 million phosphorylation sites down to 250,000 plausible ones

The atlas turns kinase-inhibitor selection into a matching problem. What is missing is evidence that the match predicts which drug works in a patient.

Publishers:phys.org

Reality

Evidence55
Adoption22
Hype gap+18
Incentives68
Confidence45
scienceOne report1 publisher

Newborn genome screening has its first saves. The unsettled part is the bill and the read-out

An Australian study flagged a fatal immune disorder in a baby before symptoms appeared. Dozens of pilots now face harder questions: cost, who interprets variants, and findings nobody can act on.

Publishers:nature.com

Reality

Evidence58
Adoption34
Hype gap+12
Incentives46
Confidence55
investOne report1 publisher

The 3.1% drug price drop has three engines, and two of them predate TrumpRx

The steepest annual decline since 1963 is being credited to most favored nation deals. The contracts are not public, the models are not live, and the index measures pharmacy receipts.

Publishers:fortune.com

Reality

Evidence64
Adoption38
Hype gap+52
Incentives74
Confidence66
productOne report1 publisher

Aircrew outrank nuclear technologists in radiation-linked cancer deaths, JAMA study finds

A Harvard-led analysis of 12.7 million US death certificates puts flight attendants and pilots first and second among 503 occupations. The authors ask for protections that match exposure.

Publishers:gizmodo.com

Reality

Evidence62
Adoption
Not scored
Hype gap+24
Incentives34
Confidence55

Earlier coverage