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Space Medicine and Crew Health

Physiological effects of spaceflight on human crews and the clinical management of them in orbit.

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scienceOne report1 publisher

Cells hit by cosmic-ray iron ions push their unhit neighbors toward tumors

Oklahoma State and UT Health researchers report that cells kept near iron-ion-struck cells, though never hit themselves, went on to form tumors in mice. If that holds in people, a Mars crew's risk lies mostly in the 97% of cells iron ions miss.

Publishers:phys.org

Reality

Evidence45
Adoption
Not scored
Hype gap+30
Incentives
Not scored
Confidence40
scienceOne report1 publisher

Crew-12 heads home in early October after crystallising cancer-targeting drugs in orbit

NASA's Crew-12, four astronauts from NASA, ESA and Roscosmos, is due back from the space station in early October. The agency's look back sets out what the crew's experiments in drug crystallisation, bone repair and quantum physics were built to test.

Publishers:nasa.gov

Reality

Evidence45
Adoption
Not scored
Hype gap+20
Incentives65
Confidence60
scienceConfirmed2 publishers

Blood from 52 space station astronauts suggests their gut bacteria start fermenting protein within weeks

University of Copenhagen researchers found blood signs of gut bacteria fermenting more protein in 52 ISS astronauts within weeks of reaching orbit. The team suspects slower digestion and says Mars crews may need countermeasures, though blood chemistry alone cannot confirm the cause.

Reality

Evidence60
Adoption
Not scored
Hype gap+35
Incentives30
Confidence60
scienceOne report1 publisher

NASA and ESA will share Crew-13 blood draws to study clotting in weightlessness

NASA and ESA will coordinate blood draws from Crew-13 astronauts in a joint clotting study, one of six human studies on the mission. The study asks why weightlessness disturbs venous blood flow in some astronauts but not others, and answering that depends on how many crew take part.

Publishers:nasa.gov phys.org

Reality

Evidence60
Adoption
Not scored
Hype gap+10
Incentives35
Confidence65
scienceOne report1 publisher

Simulated weightlessness swells the nucleus of live human cells in an NYU rotator

Alexandra Zidovska's group at NYU built a rotating stage that cancels most of the fluid flow such rigs create, then compared cells under simulated weightlessness, under strong flow, and untouched for 24 hours.

Publishers:phys.org

Reality

Evidence58
Adoption
Not scored
Hype gap+15
Incentives52
Confidence60
scienceOne report1 publisher

Exercise keeps 14 astronauts' hearts within Mars-tolerable range, station echocardiograms show

A Circulation study co-led by UT Southwestern measured astronaut hearts during six-month station missions, the window earlier work left blank, and reports the early shrinkage stayed inside what Mars-level gravity would demand.

Publishers:phys.org

Reality

Evidence55
Adoption45
Hype gap+30
Incentives60
Confidence58
scienceOne report1 publisher

Second generation of mice showed reduced fertility after mothers spent 42 days on the ISS

Twenty female mice spent 42 days on the International Space Station, conceived after landing, and produced two further generations with fewer litters, smaller litters and lower ovarian hormone levels. Their own litters were only slightly small.

Publishers:livescience.com

Reality

Evidence62
Adoption
Not scored
Hype gap+22
Incentives34
Confidence57
scienceOne report1 publisher

Heart changes in 13 astronauts stabilized in orbit and reversed after they landed

A Circulation study followed cardiac structure through full six-month missions using ultrasound the crews ran themselves. Because every astronaut completed the prescribed exercise, it cannot separate the countermeasure from the adaptation.

Publishers:statnews.com

Reality

Evidence62
Adoption40
Hype gap+18
Incentives60
Confidence55
scienceOne report1 publisher

Fram2's crew took usable diagnostic X-rays in orbit after four hours of training

MinXray's portable unit flew on the private Fram2 mission in March 2025, and radiologists on the ground called the crew's images clear enough to diagnose from. The report appeared in Radiology in July 2026.

Reality

Evidence60
Adoption22
Hype gap+25
Incentives55
Confidence58
scienceOne report1 publisher

Parabolic flight shifted four women's vaginal microbiomes more than their oral ones

A first-of-its-kind study of four fliers reports the vaginal community moving while the oral one mostly held still, which is enough to justify a bigger orbital experiment and not enough to tell a flight surgeon what to sample.

Publishers:phys.org

Reality

Evidence26
Adoption8
Hype gap+38
Incentives62
Confidence52
scienceOne report1 publisher

Astronaut constipation gets a blood marker, and a Mars-length problem attached

A NASA-backed study of 52 ISS crew members found gut bacteria switching to protein fermentation within weeks of launch, producing compounds the authors tie to kidney and cognitive harm.

Publishers:livescience.com

Reality

Evidence62
Adoption22
Hype gap+26
Incentives48
Confidence55