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Topic

Comparative Genomics

Cross-species genomic and functional data used to reconstruct ancestral states and infer trait mechanisms.

Current stories

scienceConfirmed10 publishers

Sequencing of 194-year-old Jonathan the tortoise turns up 287 gene changes unique to him

Kallel-led researchers found 287 gene changes unique to Jonathan, the 194-year-old Aldabra tortoise, touching DNA repair, inflammation, insulin and cancer. Because the baseline was just four other tortoises, the 287 are candidates to explain his slow ageing.

Perspective Coverage

10 publishers
Builder
Builder 61%
Operator
Operator 19%
Investor
Investor 20%

Reality

Evidence58
Adoption
Not scored
Hype gap+35
Incentives45
Confidence62
scienceOne report1 publisher

The little brown bat's cells answered a lethal dose by turning up cell-death genes

A Berkeley team's first analysis of eight Myotis genomes, out in Nature, links longer bat lifespans to higher levels of cancer-fighting genes. The same lab's dish experiments point at how damaged cells get cleared.

Publishers:sciencedaily.com

Reality

Evidence46
Adoption
Not scored
Hype gap+34
Incentives72
Confidence55
scienceOne report1 publisher

Antarctic soil hands microbiology's 'everything is everywhere' rule a controlled exception

Nick Dragone's team sequenced more than 100 Antarctic Arthrobacter strains and found 90 percent with no match anywhere else, a result whose strength rests on how thoroughly the rest of the world has been sampled.

Publishers:phys.org

Reality

Evidence46
Adoption
Not scored
Hype gap+26
Incentives62
Confidence44
scienceOne report1 publisher

Testis-biased genes predict whether a gecko's new sex chromosome becomes a Z or an X

Across 22 gecko species, and again across 39 vertebrates, ancestral chromosomes rich in testis-expressed genes became Zs while the gene-poor ones became Xs. That is a rule with a direction, so it can be tested elsewhere.

Publishers:phys.org

Reality

Evidence52
Adoption
Not scored
Hype gap+18
Incentives62
Confidence44
scienceConfirmed3 publishers

Bats' virus defenses and their long, cancer-free lives may be the same genes doing double duty

A Nature study of eight Myotis genomes argues pathogen adaptation, longevity and cancer resistance run through shared, pleiotropic genes, redirecting where aging and cancer researchers might look.

Perspective Coverage

3 publishers
Builder
Builder 48%
Operator
Operator 29%
Investor
Investor 23%

Reality

Evidence82
Adoption22
Hype gap+18
Incentives45
Confidence74