The Lancet is a leading peer-reviewed British medical journal publishing research, commissions, and models spanning clinical trials to global health policy.
Lancet Commission experts modeled 17 global health threats through 2100 and rated two, malicious AI and nuclear conflict, as carrying extinction potential. Obesity leads on avoidable burden at 23.1 billion disability-adjusted life-years, the gap between best and worst case by 2100.
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Google's AMIE chatbot interviewed 98 patients ahead of urgent-care visits. Its differential matched the doctor's final diagnosis 90 percent of the time. A supervising physician watched every conversation, so the Lancet study is an early safety check inside a working clinic.
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Lancet Commission experts rank malicious AI use, including bioweapons, alongside nuclear war as the threats that could end humanity by 2100. Their report says each of its 17 risks has a realistic route to action, so AI misuse reaches policymakers as a problem with a solution.
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University of Bristol researchers set out five steps in The Lancet to protect health from a super El Niño expected late this year. Most of the steps ask for evidence first, because the extra health burden El Niño adds to climate change is still largely unmeasured.
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Toronto and UCSF researchers report that older women with higher levels of 16 menopause-linked molecules were 15 percent likelier to develop Alzheimer's. The authors see menopause as a window for early-warning testing, though the evidence so far is a correlation.
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Florian Naudet's team re-ran two Prozac meta-analyses without one 2006 trial of 40 Iranian children, and the drug's large edge in child depression vanished. The authors want guideline committees to re-weigh Prozac's recommendation but are not asking doctors to stop prescribing.
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Eli Lilly's retatrutide cut body weight by more than 20% on average at its top dose in an 80-week phase 3 trial of 1,152 people with type 2 diabetes. Lilly calls that a first for the field, and it gives the four- and five-receptor drugs now in development a figure to beat in patients with diabetes.
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Sustentarea at the University of Sao Paulo mapped under-5 stunting and overweight against per capita emissions for Brazilian municipalities from 2008 to 2019. It shows where the problems overlap, though local emissions cannot test the climate-to-diet chain said to link them.
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The World Health Summit Academic Alliance and The Lancet have seated 30 commissioners from 22 countries to work out how academic institutions should be designed and governed, with recommendations due in 2028.
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The ISGlobal-led study puts avertable deaths at 6.6 to 29.5 million by 2030, and that four-and-a-half-fold spread turns on which tax is levied and at what rate rather than on any statistical bound.
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A new WHO burden estimate covering 14 parasitic diseases finds nematodes alone caused 143 million foodborne cases, with two disease groups accounting for nearly the whole total.
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