Company
New York City cancer hospital and research centre whose Sloan Kettering Institute covers cancer biology, immunology and genomics alongside patient care.
In a study of 100,000+ people, Rockefeller University researchers found those with active brown fat less affected by type 2 diabetes, depression and anxiety. Protection rose with the amount of active fat, but a retrospective design cannot show that the fat is the cause.
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Memorial Sloan Kettering scientists found that blocking MEK let exhausted cancer-fighting T cells conserve energy and persist near tumors in animal studies. Because MEK inhibitors are already FDA-approved, the lab says the approach could be tested in people soon.
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Memorial Sloan Kettering researchers found each extra 100g of sugary food on antibiotics went with an average 24% bigger gut-diversity drop in 158 patients. Mouse experiments point to sugar feeding a pathogen bloom, though the patient result is an association drawn from hospital meal logs.
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Memorial Sloan Kettering researchers used nanoparticles to kill a scar-driving macrophage subset, restoring immunotherapy in mice with liver and lung cancer. The Science paper points to the tumor's fibrotic barrier as a route past immunotherapy resistance.
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AlphaGenome Atlas scores every possible single-letter change in the human genome and hands the result to anyone with a browser, which moves the scarce input from computing a prediction to confirming one. Price and drug-developer partnerships go unmentioned in the release.
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